Objectives for the whole module:
Upon completion of this part, students should be able to:
- Describe the Bacillus and Clostridium genera and list their pathogenic species;
- Describe the mode of transmission, clinical findings, the morphology and identification (diagnostic tests) for each of the pathogenic Gram positive spore forming rods.
- List some effective antibiotics against Bacillus and Clostridium pathogenic species.
Components: two lectures; online exercises and feedback form plus innovation, creativity and the use of higher-order thinking patterns (see below):
Lecture 1: The Bacillus Genus
Objectives for lecture 1:
- Describe the Bacillus genus and list their pathogenic species;
- Describe the mode of transmission, clinical findings, the morphology and identification (diagnostic tests) for each of the pathogenic Bacillus species.
- List some effective antibiotics against Bacillus pathogenic species.
Click Here for Bacillus Online Exercises & Feedback Form
إنقر هنا للوصول لتمارين البسلاي الالكترونية وصندوق المقترحات
Lecture 2: The Clostridium Genus
Objective for lecture 2:
- Describe the Clostridium genus and list their pathogenic species;
- Describe the mode of transmission, clinical findings, the morphology and identification (diagnostic tests) for each of the pathogenic Clostridium species.
- List some effective antibiotics against Clostridium pathogenic species.
د. محمد بن عبد الله آل قمبر 
Salam Dear Students,
Please start commenting and interacting. Enrich the course with your ideas, relevant science, articles, news and any questions you have.
I am also waiting for your homework. Note there are two exercise forms for this module. One for the Bacillus genus lecture, and the other for the Clostridium genus.
Regards and Best Wishes
Salam everyone…
I found this:
Bacillus anthracis infection among people who inject drugs in Scotland http://go.usa.gov/pk73
and i find this:
Bacillus probiotics improve digestion and help restore proper function: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC383048/
Some bad some good bacteria
🙂 🙂
😉
Good and bad in the one genus
هل يمكن للجراثيم أن تقاوم المطهرات كما تقاوم المضادات الحيوية
Dear Fouad Ahemed,
Not usually, disinfectants are chemicals that can kill all types of cells and include bleach, phenol and alcohol. Antibiotics are selectively toxic and kill selected cells while sparing others, and therefore resistance can develop against antibiotics more than disinfectants.
المطهرات غالباً مواد كيميائية يمكن أن تقتل جميع أنواع الخلايا لو تعرضت لها وتشمل الفينول والكحول وفي المقابل المضادات الحيوية هي انتقائية السُمية وتقتل الخلايا المحددة في حين تُجنب خلايا اخرى، وبالتالي المقاومة يمكن أن تتطور للمضادات الحيوية اسرع
Thank you Doctor
Thank you Doctor.
Why b.cereus is not causing systematic infection like anthrax
Dear Hassan Abdullah,
Good afternoon. B. cereus lack the virulence genes that allow it to be able to cause many systematic infections. That is, B.cereus can cause systematic infections sometimes, but this is rare. Remember that B. anthracis that cause anthrax carry many virulence genes that allow it to produce toxins such as the lethal factor (LF), and the edema factor (EF). Yet, B. cereus can sometime cause systemic infections in people with weak immune system or underlining diseases. See for example these two reports:
http://www.ncbi.nlm.nih.gov/pubmed/23927823
http://www.ncbi.nlm.nih.gov/pubmed/23994997
كيف أحصل على النطق الصحيح لأسماء الجراثيم يادكتور ألامر صعب
ولكم مني وزملائي كثير الشكر وعظيم التقدير على تجاوبك الدائم بالكلية وخارجها
Dear Mohammed khoshaim,
Please visit this website: (http://www.atsu.edu/faculty/chamberlain/Website/studio.htm)
which include audio clips for the pronunciation of microbes’ names.
مرحباً بكم، ارجو زيارة الموقع التالي المتضمن تسجيلات صوتيه لاسماء الجراثمية للإستماع للنطق الصحيح
http://www.atsu.edu/faculty/chamberlain/Website/studio.htm
وفقكم الله
why gangare happen in people with diabetes more?
Dear Jumaan,
Diabetes mellitus is known to damage cells and reduce immunity. Also, diabetes mellitus damage blood vessels and can cause ischemia. As a consequence, anaerobic bacteria, like clostridium perfringens, can grow and produce their toxins and cause diseases easier in patients with diabetes mellitus. Hope this answer your question. Regards
Hello. What can we do to prevent antibiotic-associated diarrhea in people needing antibiotics, is there a way? thanlk u..
Dear AB,
It can be difficult to prevent the infection. One approach is to reduce or avoid the use of antibiotics whenever possible. Another, is to use probiotics, bacterial replacement therapy and fecal transplantations. Note, today we have fecal pills to be used to manage antibiotic-associated diarrhea and pseudomembranous colitis. Studies have demonstrated efficacy of fecal transplantation in the treatment of C. difficile-associated diarrhea in patients. Please see:
http://www.uptodate.com/contents/fecal-microbiota-transplantation-in-the-treatment-of-recurrent-clostridium-difficile-infection
thanks doctor. how can we sterilize rice to kill spores to stop toxin disease by Bacillus ceres.
Dear Mohammed,
It is difficult to sterilize food, specially when we have spores involved. Remember that spores are resistant to the heat of cooking and many chemical disinfectants. If you want to sterilize rice and kill all spores you will need to autoclave or radiate !! This will be very expensive. Nonetheless, it is ok to have few spores ingested, as long as they are not allowed to germinate and produce their toxins. Therefore, basic food safety principles should be sufficient to prevent any problems. You can have a look at the website below to remind yourself with these safety principles (لهيئة الغذاء والدواء):
http://old.sfda.gov.sa/Ar/Food
This is useful Doctor thank you very much
thank you
thank your doctor